"Genesis is a great system with terrific primary stability and improved performance allowing an overwhelming sense of clinical confidence."
Dr. Michael Buchanon, North Dakota

Stabilizing Dual Thread Design

Micro threads minimize pressure on the cortical bone while aggressive macro threads offer primary mechanical stability, especially in soft bone—providing optimal insertion torque and immediate function in all bone types.

Bone-Like Biomimetic Surface

The BioSpark™ proprietary anodic spark deposition (ASD) process produces a charged macro-micro-nano textured surface that mimics the chemical composition and structure of natural bone.1

Natural Long-Term Aesthetics

The dark gray shadow of traditional titanium implants are no longer a concern with the AnaTite™ Pink Collar and Abutments, featuring a natural, uniformly pink hue that closely resembles the peri-implant mucosa.

World-Class Support

Keystone Dental offers superior training, support and service for all our implant systems, biomaterials and software. Our knowledgeable customer service team is available by phone or email to accommodate your questions and requests.

Characteristics of an Advanced Surface Design

  1. Hydrophilic Surface attracts blood to site stimulating angiogenesis
  2. Charged Calcium & Phosphorous Ions fuel osteoblastic activity
  3. Nanosurface Topography supports adhesion and proliferation of osteoblasts

What is Biomimesis

We took our inspiration for Genesis from nature.

The approach is called biomimesis. It comes from the Greek words bios, meaning life and mimesis, meaning to imitate.

Technically, biomimesis is the study of the structure and function of biological systems for product design and engineering inspiration. For your patients, it means a more natural-looking smile.

Keystone Dental embraces biomimesis as a design philosophy. You’ll see this philosophy come to life in our Genesis implant system. Design features such as the BioSpark Surface and the AnaTite Pink Aesthetics were developed utilizing biomimetic principles.

The nanocrystalline structure of the BioSpark surface mimics the crystalline structure of the bone matrix.

The area in green is BioSpark.
The area in red is Bone Matrix.

† Data on file, Samo Biomedica, 2010.

Building a Biomimetic Surface

How do Genesis implants gain a hydrophilic and positively charged macro-micro-nano textured surface to facilitate faster osseointegration as compared to macro-micro textured titanium surfaces?*

Creating Macro-Micro Surface Roughness

The body of the implant is roughened and double-etched creating the macro-micro surface.

Anodization & the
AnaTite Process

Genesis implants are anodized through an electrochemical process to generate the natural titanium oxide surface, turning the implant to a uniform pink color.

The BioSpark Process

The anodic spark deposition (ASD) process (also known as microarc oxidation and glow discharge deposition) creates controlled ‘sparking’ to produce a uniform nano-roughened surface, enriched with charged calcium and phosphorous ions.

The Result: Genesis,
The Biomimetic Implant System

A surface composition that offers a macro-micro-nano texture that mimics natural bone, combined with a moderately roughened pink collar to maximize bone levels7 and enhance aesthetic outcomes.

* The BioSpark™ surface facilitates faster osseointegration, as demonstrated by significant bone-to-implant-contact (BIC) in the cortical bone of sheep** at 4 weeks compared to machined or blasted titanium2,3 and as further supported by in vitro studies4,6, which yielded the following individual results:

  • Significant increase in cellular metabolic activity over 1 to 7 days in simulated body fluid on cp-Ti disks treated with BioSpark when compared to machined titanium.4
  • Significant increase in osteoblast proliferation over 1 to 3 days on cp-Ti disks treated with BioSpark when compared to machined or acid etched titanium.5
  • Early fibronectin absorption and enhanced adhesion, proliferation, and differentiation of osteoblasts at 24, 48 and 72 hours on cp-Ti disks treated with BioSpark when compared to other anodic spark deposition (ASD) surfaces.6

** Results in animal studies are not necessarily predictive of human clinical results.

References
  1. LeGuehennec L, Soueidan A, Layrolle P, Amouriq Y. Surface treatments of titanium dental implants for rapid osseointegration. Dental Materials. 23;2007:844-854.
  2. Giavaresi G, Chiesa R, Fini M, Sandrini E. Effect of a Multiphasic Anodic Spark Deposition Coating on the Improvement of Implant Osseointegration in the Osteopenic Trabecular Bone of Sheep. The Int’l Jrnl of Oral & Maxillofacial Implants 23(4); 2008; 659-668.
  3. Giavaresi G, et al, A novel multiphasic anodic spark deposition coating for the improvement of orthopedic implant osseointegration: An experimental study in the cortical bone of sheep. J Biomed Mater Res Part A: 2007; 1022-1031.
  4. Sandrini E, Giordano C, Busini V, Signorelli E, Cigada A. Apatite formation and cellular response of a novel bioactive Titanium. Journal of Materials Science: Materials in Medicine 18; 2007; 1225–1237
  5. Giordano C, Sandrini E, Del Curto B, Signorelli E, Rondelli G, Di Silvio L. Titanium for osteointegration: Comparison between a novel biomimetic treatment and commercially exploited surfaces. Journal of Applied Biomaterials & Biomechanics 2004; 2:35-44.
  6. Sandrini E, Morris C, Chiesa R, Cigada A, Santin M. In vitro assessment of the osteointegrative potential of a novel multiphase anodic spark deposition coating for orthopaedic and dental implants. J Biomed Mater Res Part B: Appl Biomater. 73B;2005:392-399.
  7. Zetterqvist L. et al. A Prospective, Multicenter, Randomized-controlled 5 year study of H Implants for incidence of Peri-implantitis. J Periodontology 2009 Dec 23 (14pp.).
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