"Genesis is a great system with terrific primary stability and improved
performance allowing an overwhelming sense of clinical confidence."
Dr. Michael Buchanon, North Dakota
Stabilizing Dual Thread Design
Micro threads minimize pressure on the cortical bone while aggressive macro threads
offer primary mechanical stability, especially in soft bone—providing optimal insertion
torque and immediate function in all bone types.
Bone-Like Biomimetic Surface
The BioSpark™ proprietary anodic spark deposition (ASD) process produces a
charged macro-micro-nano textured surface that mimics the chemical composition and
structure of natural bone.1
Natural Long-Term Aesthetics
The dark gray shadow of traditional titanium implants are no longer a concern with
the AnaTite™ Pink Collar and Abutments, featuring a natural, uniformly pink
hue that closely resembles the peri-implant mucosa.
World-Class Support
Keystone Dental offers superior training, support and service for all our implant
systems, biomaterials and software. Our knowledgeable customer service team is
available by phone or email to accommodate your questions and requests.
Characteristics of an Advanced Surface Design
- Hydrophilic Surface attracts blood to site stimulating angiogenesis
- Charged Calcium & Phosphorous Ions fuel osteoblastic activity
- Nanosurface Topography supports adhesion and proliferation of osteoblasts
What is Biomimesis
We took our inspiration for Genesis from nature.
The approach is called biomimesis. It comes from the Greek words bios, meaning life
and mimesis, meaning to imitate.
Technically, biomimesis is the study of the structure and function of biological
systems for product design and engineering inspiration. For your patients, it means
a more natural-looking smile.
Keystone Dental embraces biomimesis as a design philosophy. You’ll see this philosophy
come to life in our Genesis implant system. Design features such as the BioSpark
Surface and the AnaTite Pink Aesthetics were developed utilizing biomimetic principles.
The nanocrystalline structure of the BioSpark surface mimics the crystalline structure
of the bone matrix†.
The area in green is BioSpark.
The area in red is Bone Matrix.
† Data on file, Samo Biomedica, 2010.
Building a Biomimetic Surface
How do Genesis implants gain a hydrophilic and positively charged macro-micro-nano
textured surface to facilitate faster osseointegration as compared to macro-micro
textured titanium surfaces?*
Creating Macro-Micro Surface Roughness
The body of the implant is roughened and double-etched creating the macro-micro
surface.
Anodization & the
AnaTite Process
Genesis implants are anodized through an electrochemical process to generate the
natural titanium oxide surface, turning the implant to a uniform pink color.
The BioSpark Process
The anodic spark deposition (ASD) process (also known as microarc oxidation and
glow discharge deposition) creates controlled ‘sparking’ to produce a uniform nano-roughened
surface, enriched with charged calcium and phosphorous ions.
The Result: Genesis,
The Biomimetic Implant System™
A surface composition that offers a macro-micro-nano texture that mimics natural
bone, combined with a moderately roughened pink collar to maximize bone levels7
and enhance aesthetic outcomes.
* The BioSpark™ surface facilitates faster osseointegration, as demonstrated by
significant bone-to-implant-contact (BIC) in the cortical bone of sheep** at 4 weeks
compared to machined or blasted titanium2,3 and as further supported
by in vitro studies4,6, which yielded the following individual results:
- Significant increase in cellular metabolic activity over 1 to 7 days in simulated
body fluid on cp-Ti disks treated with BioSpark when compared to machined titanium.4
- Significant increase in osteoblast proliferation over 1 to 3 days on cp-Ti disks
treated with BioSpark when compared to machined or acid etched titanium.5
- Early fibronectin absorption and enhanced adhesion, proliferation, and differentiation
of osteoblasts at 24, 48 and 72 hours on cp-Ti disks treated with BioSpark when
compared to other anodic spark deposition (ASD) surfaces.6
** Results in animal studies are not necessarily predictive of human clinical results.
References
- LeGuehennec L, Soueidan A, Layrolle P, Amouriq Y. Surface treatments of titanium
dental implants for rapid osseointegration. Dental Materials. 23;2007:844-854.
-
Giavaresi G, Chiesa R, Fini M, Sandrini E. Effect of a Multiphasic Anodic Spark
Deposition Coating on the Improvement of Implant Osseointegration in the Osteopenic
Trabecular Bone of Sheep. The Int’l Jrnl of Oral & Maxillofacial Implants 23(4);
2008; 659-668.
- Giavaresi G, et al, A novel multiphasic anodic spark deposition coating for the
improvement of orthopedic implant osseointegration: An experimental study in the
cortical bone of sheep. J Biomed Mater Res Part A: 2007; 1022-1031.
- Sandrini E, Giordano C, Busini V, Signorelli E, Cigada A. Apatite formation and
cellular response of a novel bioactive Titanium. Journal of Materials Science: Materials
in Medicine 18; 2007; 1225–1237
- Giordano C, Sandrini E, Del Curto B, Signorelli E, Rondelli G, Di Silvio L. Titanium
for osteointegration: Comparison between a novel biomimetic treatment and commercially
exploited surfaces. Journal of Applied Biomaterials & Biomechanics 2004; 2:35-44.
- Sandrini E, Morris C, Chiesa R, Cigada A, Santin M. In vitro assessment of the osteointegrative
potential of a novel multiphase anodic spark deposition coating for orthopaedic
and dental implants. J Biomed Mater Res Part B: Appl Biomater. 73B;2005:392-399.
- Zetterqvist L. et al. A Prospective, Multicenter, Randomized-controlled 5 year study
of H Implants for incidence of Peri-implantitis. J Periodontology 2009 Dec 23 (14pp.).
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