DynaMatrix® Extracellular Membrane
DynaMatrix is a barrier membrane for use in guided bone and guided tissue
As the only intact extracellular membrane (ECM) designed to remodel soft tissue,
DynaMatrix integrates the three essential biological components required for natural
- A matrix scaffold that retains its three-dimensional
structure to facilitate soft tissue regeneration.1
- Signaling proteins, within the membrane, that communicate
with the body to help stimulate the natural healing process.2
- Once implanted, these components facilitate the recruitment of
the body’s own cells, in effect allowing the body to restore itself.
Unlike collagen membranes, which are broken down and eliminated by the body, DynaMatrix
completely remodels into strong, fully vascularized tissue.3 Once the
healing process is complete, DynaMatrix is undetectable and becomes an indistinguishable
component of the patient’s natural gingival tissue.4
Excellent Handling & Ease of Use
Because it is an intact extracellular matrix, DynaMatrix may be left exposed in
the surgical site. This also allows for rapid vascularization. DynaMatrix is pliable
enough to drape easily and flexible enough to be cut, rolled, folded, tacked or
Natural Healing Jumpstart
The active proteins and molecules—including growth factors, glycoproteins and glycosaminoglycans
(GAGs)—found within DynaMatrix communicate with the body by signaling surrounding
tissue to grow across the scaffold. These active proteins also support the natural
healing process by attracting cells and nutrients to the wounded area.
Accepted Like Native Tissue
DynaMatrix does not initiate a strong inflammatory response like other foreign materials.
Histology shows that the tissue generated by DynaMatrix is similar to tissue generated
by autogenous graft, with mature connective tissue (CT) covered by keratinized epithelium
Unlike reconstituted materials, DynaMatrix starts strong and becomes stronger and
more tear-resistant when hydrated. The same SIS technology is used in applications
where high tensile strength is required, such as hernia repair.
- Hodde J, Janis A, Ernst D, et al. “Effects of sterilization on an extracellular
matrix scaffold: part I. Composition and matrix architecture.” J Mater Sci Mater
- Hodde JP, Ernst DM, Hiles MC.”An investigation of the long-term bioactivity of endogenous
growth factor in OASIS Wound Matrix.” J Wound Care. 2005 Jan;14(1):23-5.
- Woo SL, Takakura Y, Liang R, et al. “Treatment with bioscaffold enhances the fibril
morphology and the collagen composition of healing medial collateral ligament in
rabbits.” Tissue Eng. 2006;12(1):159-166.
- Nevins M, Nevins ML, Carmelo M, et al. “The Clinical Efficacy of DynaMatrix Extracellular
Membrane in Augmenting Keratinized Tissue”. Int J Periodontics Restorative Dent