DynaMatrix Plus is a high-performing clinical alternative to connective tissue grafts
and eliminates the need to harvest tissue from the patient’s oral cavity. At twice
the thickness of standard DynaMatrix, DynaMatrix Plus has been engineered to generate
tissue of increased depth for root coverage and tissue bulking procedures.
Featuring DynaMatrix Technology
As the only intact extracellular membrane (ECM) designed to remodel soft tissue,
DynaMatrix integrates the three essential biological components required for natural
- A matrix scaffold that retains its three-dimensional
structure to facilitate soft tissue regeneration.1
- Signaling proteins, within the membrane, that communicate
with the body to help stimulate the natural healing process.2
- Once implanted, these components facilitate the recruitment of
the body’s own cells, in effect allowing the body to restore itself.
DynaMatrix completely remodels into strong, fully vascularized tissue.3
Once the healing process is complete, DynaMatrix is undetectable and becomes an
indistinguishable component of the patient’s natural gingival tissue.4
Natural Healing Jumpstart
Unlike acellular dermal matrices, DynaMatrix Plus communicates with the body, signaling
surrounding tissue to grow across the scaffold and generate thick, vascularized
tissue, while active proteins and molecules—including growth factors, glycoproteins
and glycosaminoglycans (GAGs)—support the natural healing process by stimulating
angiogenesis and attracting cells and nutrients to the wounded area.
Accepted Like Native Tissue
DynaMatrix does not initiate a strong inflammatory response like other foreign materials.
Histology shows that the tissue generated by DynaMatrix is similar to tissue generated
by autogenous graft, with mature connective tissue (CT) covered by keratinized epithelium
Ease of Use
DynaMatrix Plus is easy to handle: it is pliable enough to drape easily and flexible
enough to be cut, rolled, folded, tacked or sutured. Also, because DynaMatrix Plus
is composed of natural extracellular matrix, it will not shrink or stretch in the
Unlike reconstituted materials, DynaMatrix starts strong and becomes stronger and
more tear-resistant when hydrated. The same SIS technology is used in applications
where high tensile strength is required, such as hernia repair.
- Hodde J, Janis A, Ernst D, et al. “Effects of sterilization on an extracellular
matrix scaffold: part I. Composition and matrix architecture.” J Mater Sci Mater
- Hodde JP, Ernst DM, Hiles MC.”An investigation of the long-term bioactivity of endogenous
growth factor in OASIS Wound Matrix.” J Wound Care. 2005 Jan;14(1):23-5.
- Woo SL, Takakura Y, Liang R, et al. “Treatment with bioscaffold enhances the fibril
morphology and the collagen composition of healing medial collateral ligament in
rabbits.” Tissue Eng. 2006;12(1):159-166.
- Nevins M, Nevins ML, Carmelo M, et al. “The Clinical Efficacy of DynaMatrix Extracellular
Membrane in Augmenting Keratinized Tissue”. Int J Periodontics Restorative Dent