DynaBlast® Demineralized Bone Matrix with Cancellous Bone Chips

DynaBlast is an allograft material that contains both demineralized and mineralized bone in a proprietary, Reverse Phase Medium carrier. DynaBlast stimulates new bone growth while providing a natural structural scaffold to support new bone formation.

Dependable Bone Growth

DynaBlast is a powerful 2-in-1 combination of osteoconductive and osteoinductive elements1-3 to promote new bone growth. Demineralized bone provides active signals to stimulate bone regeneration4 and mineralized cancellous chips provide a natural structural scaffold to encourage the attachment of osteogenic precursor cells.

Designed to Stay in Place

Our proprietary Reverse Phase Medium carrier thickens at body temperature, resists both irrigation and suction and allows for guided clot formation and easy vascularization. DynaBlast stays in place, with no bone chips migrating from the site—alleviating possible irritation and patient concern.

Easy Handling

DynaBlast is available as a moldable putty or a flowable paste in a prefilled syringe. Both are premixed for easy application without refrigeration—no additional time required for thawing, mixing or setting the material.

Committed to Quality

DynaBlast uses tissue only from suppliers that comply with all tissue banking standards as provided by the Food and Drug Administration (FDA), the American Association of Tissue Banks (AATB) and the Clinical Laboratory Improvement Amendments (CLIA). Every lot of demineralized bone matrix (DBM) used in DynaBlast has been thoroughly tested in a quantitative in vitro assay to ensure its osteoinductive properties.3

References
  1. Clokie C, Urist MR. Bone Morphogenetic Protein Excipients: Comparative Observations on Poloxamer. Plast Reconst Surg 2000;105: 628.
  2. Coulson R, Clokie C, Peel S. Collagen and a Thermally Reversible Poloxamer Deliver Demineralized Bone Matrix (DBM) and Biologically Active Proteins to Sites of Bone Regeneration. Proc Portland Bone Symp 1999. p. 619-637.
  3. Kay, JF. Validated Assay for Measuring Osteoinductivity of Human Demineralized Bone Matrix, Integra OrthoBiologics Publication.
  4. Urist, MR. Bone: Formation by Autoinduction. Science; 150: 893, 1965.
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